Asociación entre la exposición al frío y el asma: revisión sistemática y meta-análisis, 1965-2015

Objectives: to conduct a systematic review and meta-analysis of observational expe- rimental studies that explore the relation between asthma cold exposure. Materials methods: experimental pu- blished up August 2015 in Pubmed, Embase Lilacs. Two researchers selected measured occurrence individuals exposed different environmen- tal temperatures. A used RevMan 5.3’s random effects model calculate summary weighted Odds Ratio with 95% confidence intervals, sensitivity analysis identified influence each study. Subsequent subgroup analyses measures by type exposure study design. Additional hetero- geneity risk bias. Results: we found 86 measuring asthma. We included 11.6% (10/86) an association all (ORw 2.0 95%CI 1.28-3.14), 3.8 IC95% 1.70-8.86), environmental air 1.59 1.10-2.30). The had high bias statistical heteroge- neity [I2 : 63.1% (27%-81.4%)]. Conclusions: results support hypothesis This encourages concepts proposed traditional medi- cine establish its benefits on prevention care respiratory diseases, such as